"Do we imagine that complete control over our biological fates will necessarily make us happier? Perhaps it will. But one can as easily imagine that there might be little room for uninhibited joy or exuberance in such a world. More likely it will be a tightly wound world, saturated with bitterness and anxiety and mutual suspicion, in which life and health will be guarded with all the ferocity of Ebenezer Scrooge guarding his money. Growing mastery means growing responsibility, and the need to assign blame, since nothing happens by chance. Some of the blame will be directed at the parents, politicians, doctors, and celebrities who make plausible villains, or conspiracy theories that explain why someone else is always at fault. But much of the blame will devolve upon ourselves, since in being set free to choose so much about our lives, we will have no one else to blame when we make a complete mess of things."
Wilfred McClay, "Against Mastery," in The Hedgehog Review